The Centre for Addiction and Mental Health (CAMH) Brain Health Imaging Centre

Toronto,  ON 
Canada
http://www.camh.ca/imaging
  • Booth: NP8


The CAMH Brain Health Imaging Centre (BHIC) is a global leader in research for all facets of brain health.

The CAMH Brain Health Imaging Centre (BHIC) is a global leader in research for all facets of brain health, ranging from psychiatric disorders and addictions to neurological diseases, traumatic brain injuries and mental health consequences. The Centre plays a pivotal role in empowering scientists worldwide to explore new directions in brain chemistry, structure, function, and behavior linked to brain health and neuroscience.

Founded in 1989, the BHIC boasts a rich history of fostering collaborations with academic, inductrial and pharmaceutical partners. These collaborations have provided crucial support for clinical trials by confirming target engagement, dosing regimens, pharmacokinetics, and expediting discovery of new radiopharmaceuticals and therapeutics. Through medicinal and radiochemistry, translational pre-clinical and clinical research studies, we are advancing how we understand, diagnose, and treat brain disorders.

We have significantly expanded our PET research capabilities, encompassing PET imaging, MRI, pre-clinical imaging, binding assays and digital autoradiography services, radiochemistry production facility, and neuro-science research programs. Our state-of-the-art imaging facilities empower researchers to delve into the complexities of the brain, facilitating a deeper understanding of brain health and the advancement of treatments.

Brands: About CAMH The Centre for Addiction and Mental Health (CAMH) is Canada's largest mental health teaching hospital and one of the world's leading research centres in its field. CAMH is fully affiliated with the University of Toronto and is a Pan American Health Organization/World Health Organization Collaborating Centre.


 Press Releases

  • The Centre for Addiction and Mental Health (CAMH), Canada’s largest mental health teaching hospital and a leading research centre, has joined the Canadian Nuclear Isotope Council (CNIC).

    CAMH is a global leader in brain imaging. As one of few brain imaging centres in the world that is fully dedicated to researching mental illnesses, the CAMH Brain Health Imaging Centre conducts ground-breaking research for medical imaging with positron emission tomography (PET), MRI and neuroscience while advancing innovative treatment strategies.

    With two cyclotrons, two PET scanners, and one MRI scanner on site, in addition to two fully equipped radiochemistry laboratories, a pre-clinical imaging laboratory, and a PET data analysis laboratory, CAMH is an essential part of Canada’s isotope industry and nuclear medicine community. At CAMH’s Brain Health Imaging Centre, the radiochemistry laboratories allow for GMP production of short-lived PET radiotracers for human use, and houses 17 hot cells equipped with commercial and custom-built automated synthesis units. CAMH’s on-site capabilities enable the production of over 40 PET radiopharmaceuticals for neuroimaging, of which nearly half were translated for first-in-human studies, and over 100 labelled compounds for preclinical testing.

    Using its nuclear medicine capabilities, CAMH can more accurately calculate medication doses, develop targets for treatments of illnesses such as postpartum depression, explore risk markers for Parkinson’s disease and Alzheimer’s disease, autism spectrum disorder, traumatic brain injuries and other mental health conditions such as addictions and mood disorders, and enables academic centres and pharmaceutical companies to conduct more effective drug development. CAMH aspires to help patients, families, and the community by discovering new strategies to diagnose and treat a spectrum of mental illnesses using revolutionary brain imaging tools and world-class technology and research expertise.

    As a new member of the CNIC, CAMH is joins a growing membership of organizations that are committed to securing the continued availability of isotopes for Canadian patients and pioneering research across the country.

    “Isotopes are foundational to advancing research for improved drug discovery and production, and will allow our healthcare professionals to understand more about diagnosing and treating mental illnesses that impact Canadians every day,” said James Scongack, Chair of the CNIC. “Through CNIC’s growing network of healthcare and research partners, we are working to keep Canada at the forefront of radiopharmaceutical research and development. We are pleased to welcome CAMH to collaborate on future advocacy initiatives and to raise awareness for the important work being done at Canada’s leading hospitals and research institutions like CAMH.”

    “We are delighted to become a member of the CNIC,” added Dr. Neil Vasdev, Director of the Brain Health Imaging Centre and the Azrieli Centre for Neuro-Radiochemistry at CAMH. “We will continue to carry out transformative radiochemistry research with 11C and 18F, for widespread use. We will also ensure that new radiopharmaceuticals developed at CAMH will be disseminated to researchers and patients across Canada and worldwide for all facets of brain health.”

    To learn more about CAMH, visit https://www.camh.ca/


 Products

  • Brain Imaging and Scanning Services
    The CAMH Brain Health Imaging Centre offers a comprehensive array of services, including chemistry, radiochemistry, PET, MRI, pre-clinical neuroscience, pharmacology, image analysis and study design, and regulatory submissions etc.

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  • Our Facilities and Services

    Facilities:

    Since 1989, we have significantly expanded our positron emission tomography (PET) research capabilities, encompassing PET imaging, magnetic resonance imaging (MRI), pre-clinical imaging, digital autoradiography, radiochemistry production facility, and neuro-science research programs. Our state-of-the-art imaging facilities empower researchers to delve into the complexities of the brain, facilitating a deeper understanding of brain health and the advancement of treatments.

    • PET Core Facility:  We house the Discovery MI 5 and the HRRT (High Resolution Research Tomograph).

    • Cyclotrons: We have two cyclotrons, including the dual-particle cyclotron Scanditronix MC-17 and the IBA Cyclone18 cyclotron.

    • MRI Facility: We have a 3T GE Discovery MR750 equipped with multinuclear imaging capabilities.

    • Radiochemistry Facility: Our radiochemistry laboratories are fully equipped, featuring two setups, one of which permits GMP production of short-lived positron-emitting radiotracers for human use. Our radiochemistry facility comprises a total of 17 HEPA-filtered hot cells (Comecer), housing over 12 commercial automated synthesis units (GE, Synthra, Neptis, Scansys), as well as custom-designed apparatus for non-traditional radiochemistry. We also have two laboratories for radio-metabolite analysis.

    • PET Data Analysis Laboratory: This laboratory is outfitted with contemporary radiochromatography and radiopharmaceutical analysis equipment to ensure robust quality control.

    • Preclinical Imaging Facility: We have a 3-Tesla PET-MR and PET-CT system from Mediso, tailored for preclinical imaging studies. We have a complete preclinical neuroscience research facility which also includes digital-autoradiography, fluorescent slide scanner, etc.

    We remain committed to pushing the boundaries of imaging technology and research, contributing to the advancement of neuroscience and fostering breakthroughs in understanding brain function and disorders.

    Our Services:

    Harnessing our state-of-the-art facilities and cutting-edge technology, the Brain Health Imaging Centre offers a comprehensive array of services, including chemistry, radiochemistry, PET, MRI, pre-clinical neuroscience, pharmacology (including binding assays), image analysis and study design, and regulatory submissions etc.

    Over the years, our center has facilitated these services for academia and industry.

    If you find yourself in need of imaging or scans to support your research and study endeavors, we are delighted to present the suite of services that we offer. Our team is dedicated to assisting you in every way possible, ensuring that you have access to the tools necessary for advancing your scientific pursuits.