Molecular Targeting Technologies, Inc.

West Chester,  PA 
United States
http://www.mtarget.com
  • Booth: 1715

MTTI is a clinical stage company transforming the lives of patients with severe and life-threatening diseases thru innovative targeted theranostics.

EBTATE (177Lu-EB-DOTA-TATE) radiotherapeutic targets somatostatin receptors in neuroendocrine neoplasms​.  EBTATE shows several-fold increase of blood half-life and enhanced tumor uptake over existing PRRTs. Treatments using either 1.85 or 3.7 GBq EBTATE in NET patients were well tolerated and more effective than 3.7 GBq of 177Lu-DOTA-TATE (Lutathera®). Acquired under an exclusive global license from NIH.  Enters clinical trials in the US in Q4 2020.

EBRGD (177Lu-EB-DOTA-RGD) is a selective, cancer fighting radiotherapeutic targeting αvβ3-expressing tumors. Studies are currently focused on non-small cell lung cancer and glioblastoma multiforme. Will enter clinical trials in 2021.  Acquired under an exclusive global license from NIH.

TDURA (99mTc-duramycin) radiodiagnostic targets PE, externalized in dying cells.  Clinical trials imaging colorectal tumor response to chemotherapy begin in Q3 2020.

FGA (18F-fluoroglucaric acid) radiodiagnostic targets histones to detect necrosis and apoptosis, tracking tumor response to therapy.  MTTI owns a proprietary, low cost route from FDG.  FGA holds promise in a range of diseases. 

Our Team: Seasoned executives from multinational pharmaceutical companies, each with a successful track record.

Brands: EBTATE (177Lu-EB-DOTA-TATE) EBRGD (177Lu-EB-DOTA-RGD) TDURA (99mTc-duramycin) FGA (18F-fluoroglucaric acid)

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