Scintica

The SuperArgus PET/CT is a high-performance imaging system for preclinical research. It can be configured as a combined PET/CT or PET or CT only system, and features state-of-the-art phoswich PET detectors with true depth-of-interaction (tDOI) for resolution uniformity and high sensitivity.

Available in three bore sizes, the system offers real-time imaging up to 2.5msec frame rate and advanced capabilities like sensorless cardiac gating and conscious/awake imaging.

The dual-modality configuration delivers fast scan times with superior image resolution, improved localization, and quantifiable data. In addition, the SuperArgus PET/CT has been designed with a user-friendly operator interface and easy animal positioning.

The M7 SimPET is a true simultaneous PET/MRI system utilizing the compact, permanent magnet technology in the M7 and the state-of-the-art SimPET insert. This system combines all of the benefits of the M-Series high-performance MRI systems with the state-of-the-art SimPET insert from Brightonix Imaging. The M7 System from Aspect Imaging is a self-shielded, cryogen free, MRI system that provides optimized imaging protocols for a variety of anatomical targets, providing complementary 3D anatomical images to those acquired using the SimPET insert. The SimPET “S” and “L” model insert, from Brightonix, have been optimized for use within the M7 system. Brightonix created an advanced silicon photomultiplier (SiPM) based PET insert for truly simultaneous PET/MR imaging.

The M7 system is ideally suited for MR imaging of mice, rat, and similarly sized animals, however when the SimPET insert is installed the imaging volume is limited to that of mice an similarly sized animals. The SimPET is loaded from one side of the magnet, while the M7 animal handling system with RF coil is loaded from the other. Aspect Imaging has created an RF coil optimized for use with the SimPET insert to ensure true compatibility of the two imaging modalities.

The SimPET-S and L model insert, from Brightonix, have been optimized for use within the M7 system. Brightonix has created an advanced silicon photomultiplier (SiPM) based PET insert for truly simultaneous PET/MR imaging. The engineering team at Brightonix has developed a state-of-the-art, compact, insert with low power consumption and excellent PET detector stability.

There are four (4) different models of SimPET inserts available, they vary in inner/outer diameter and axial field of view. As mentioned above the SimPET-S and SimPET-L models have been optimized for use with the M7 MRI system from Aspect Imaging; the other models are optimized for use with some of the most commonly used high-field (>3T) superconducting MRI systems from preclinical imaging. Please refer to the Brightonix Imaging Technical Specifications for complete details.

The PET workstation software is intuitive and easy to use, as is the workstation for the M7 system. The images are acquired simultaneously by both systems, and co-registered within InviCROs VivoQuant visualization software provided with the systems.

On the PET workstation the user is provided with real-time count rate monitoring, FastTomo reconstruction, along with in-line image reconstruction, all with flexible list-mode data acquisition. Calibration procedures for quality control, PET/MR geometry, as well as count rate/activity are all included within the software. Quantification is provided in Bq/ml or standardized uptake value (SUV).

The highly sensitive LSO (lutetium oxyorthosilicate) detectors provide a best-in-class sub-millimeter spatial resolution while maintaining count-rate performance to allow for both low and high-dose imaging applications.

Simultaneous acquisition of both the PET and MR images on the M7 SimPETTM allows for both spatial and temporal understanding of the PET signal with regards to the anatomical image. MRI is the gold standard in soft tissue imaging, providing not only anatomical reference for the PET signal, but may also in itself provide some additional information with regards to the tissues being imaged. Various image weighting protocol exist to help identify abnormal or pathological tissues, along with the added benefit of using specific and perhaps multi-modal contrast agents to further elucidate the molecular pathway or imaging target of interest.

The M-Series™ systems are cryogen/cooling-free, self-shielded, high-performance MRI systems based on permanent magnet technology. The M-Series systems allow preclinical researchers, with or without in-depth knowledge of MR physics, to utilize the gold standard method in soft tissue imaging without the cost, complexity, and technical burden of superconducting MRI systems. Varying-sized models allow for imaging of mice, rats, similarly sized species/samples, as well as brains of non-human primates. Based on the permanent magnet technology, there are no special infrastructure requirements, operating and maintenance costs are minimal, and they can be easily integrated into existing lab space. These 1 Tesla systems are optimized for anatomical, functional, and molecular imaging applications in cancer, cardiac, neuroscience, and multimodal imaging. The optional SimPET insert can be integrated with the M-Series for simultaneous PET/MRI acquisition.

There are no special infrastructure requirements, operating and maintenance costs are minimal, and they can be easily integrated into existing lab space. These 1 Tesla systems are optimized for anatomical, functional, and molecular imaging applications in cancer, cardiac, neuroscience, and multimodal imaging.

The animal handling system ensures the stability of the animal throughout the imaging session with easy-to-use fully integrated anesthesia, heating, and physiological monitoring systems.

The optional SimPET insert can be integrated with the M-Series for simultaneous PET/MRI acquisition.

MR contrast agents further enhance the capabilities of this imaging modality, providing invaluable insights into tissue/tumor perfusion, myocardial infarction size, and molecular targets. Gadolinium and Iron-Oxide based contrast agents can be used with the M-Series product line. These systems are ideal for contrast agent imaging as it operates at 1 Tesla (T), which embodies an increased sensitivity to the effects of Gadolinium compared to higher-field MR systems.

The TriTom imaging platform utilizes photoacoustic and fluorescence tomographies (PAFT) to enable high-resolution (up to 150 µm) non-invasive in vivo whole-body imaging in small animal models. With a practically unlimited number of excitation wavelengths per scan, the multi-modality system can simultaneously acquire photoacoustic and fluorescence data in large volumes (> 25 cm3) allowing for spectroscopic molecular analysis within the region of interest. In addition to 3D molecular maps, the TriTom enables spatially-resolved assessment of physiologic parameters in vivo, such as volumetric blood content and oxygenation without the need for contrast agents, while also providing quantitative imaging for a wide range of fluorophores and other types of molecular probes excited between 460 nm and 1320 nm. With such versatile imaging capabilities, the state-of-the-art TriTom system is ideally suited for a wide range of preclinical applications including cancer, toxicology, developmental biology, tissue engineering and regeneration, neuroscience, cardiovascular imaging, as well as in the development of drugs, therapies, and optical and fluorescent imaging probes.

The Newton 7.0 is a cutting-edge optical imaging system that offers the versatility to perform bioluminescence, fluorescence, and 3D tomographic imaging in a single device. Its user-friendly interface and advanced features make it ideal for in vivo, ex vivo, and in vitro imaging applications, as well as simultaneous imaging of multiple specimens.

The system features a state-of-the-art 4.6 megapixel CCD camera that boasts one of the largest apertures in the market. This camera provides excellent sensitivity for a variety of luciferase enzymes and fluorophores commonly used in preclinical research, allowing for fast and efficient signal acquisition. The intuitive workflow and user-friendly software are optimized for multi-user use, saving valuable time in longitudinal studies

The β-eye is the first and only PET scanner for real-time, in vivo screening of all positron emission tomography (PET) isotopes. With its high end detector technology, small footprint, and field of view suitable for whole body mouse imaging, the β-eye is a complete solution for all laboratories at any research stage.

The system is just 44cm x 46cm x 40cm in size, weighing less than 40kg. This makes it truly a desktop solution which can turn any space into an imaging lab. Despite its small footprint, the β-eye’s has a sensitivity that reaches 5%, spatial resolution near 1.2mm, and has time of flight (TOF) capabilities.

The animal handling system ensures the health and wellbeing of the imaging subject, while the Visual|eyes software suite provides a fully integrated, easy to use, platform for both image acquisition and data analysis.

The γ-eye is the first and only SPECT scanner for real-time, in vivo screening of all single photon emission computed tomography (SPECT) isotopes. With its exchangeable collimators, small footprint, and field of view suitable for whole body mouse imaging, the γ-eye is a complete solution for all laboratories at any research stage.

The system is just 44cm x 46cm x 40cm in size, weighing less than 40kg. This makes it truly a desktop solution which can turn any space into an imaging lab. Despite its small footprint, the γ-eye’s has a sensitivity of 341 cps/MBq, spatial resolution up to 1.9mm and an energy resolution below 19%.

The animal handling system ensures the health and wellbeing of the imaging subject, while the Visual|eyes software suite provides a fully integrated, easy to use, platform for both image acquisition and data analysis.

The φ-eye is a highly sensitive in vivo optical imaging system, designed for bioluminescence (BLI), fluorescence (FLI) and Cherenkov luminescence imaging (CLI). This system is used for a wide range of applications, including oncology and pharmacokinetic studies. With it’s highly sensitive detector, small footprint, and field of view suitable for imaging up to 3 mice, the φ-eye is a complete solution for all laboratories at any research stage. 

The system is just 60cm x 60cm x 60cm in size, weighing less than 60kg. This makes it truly a desktop solution which can turn any space into an imaging lab. Despite its small footprint, the φ-eye has a customizable and expandable set of filters allowing users to image most well-known probes, as well as newly developed probes. 

The animal handling system ensures the health and wellbeing of the imaging subject, while the Visual|eyes software suite provides a fully integrated, easy to use, platform for both image acquisition and data analysis.